Main Article Content
Cervical cancer that is caused by the human papillomavirus (HPV) is becoming more common. It is crucial to determine a tumor's HPV status accurately since HPV+ versus HPV- cancers represent two distinct biological and clinical entities with various therapeutic approaches. Oncoproteins E6 and E7, which interfere with cellular senescence and ultimately promote carcinogenesis, are encoded by high-risk HPV subtypes. Utilizing this well-established carcinogenic pathway, current HPV detection techniques identify HPV at various biological stages. A summary of the review on HPV replication, pathogenesis, epidemiology, and detection technologies, as well as their current or prospective future roles in management and prognostication, is provided in this review article.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.