DETECTION AND CHARACTERIZATION OF HIGH RISK HUMAN PAPILLOMA VIRUS E2 AND E6 GENES FROM CERVICAL CANCER TISSUES

Authors

  • Dr. Hasan Al-hayali Cyprus International University- Department of Bioengineering Isfahan University of Technology- University of Isfahan -Faculty of Biological Sciences and Technology-Department of Cell and Molecular Biology and Microbiology

DOI:

https://doi.org/10.17605/OSF.IO/BQZWV

Keywords:

human papillomavirus, replication and diagnostic methods

Abstract

Cervical cancer that is caused by the human papillomavirus (HPV) is becoming more common. It is crucial to determine a tumor's HPV status accurately since HPV+ versus HPV- cancers represent two distinct biological and clinical entities with various therapeutic approaches. Oncoproteins E6 and E7, which interfere with cellular senescence and ultimately promote carcinogenesis, are encoded by high-risk HPV subtypes. Utilizing this well-established carcinogenic pathway, current HPV detection techniques identify HPV at various biological stages. A summary of the review on HPV replication, pathogenesis, epidemiology, and detection technologies, as well as their current or prospective future roles in management and prognostication, is provided in this review article.

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Published

2022-11-09

Issue

Vol. 3 No. 11 (2022): agir

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

DETECTION AND CHARACTERIZATION OF HIGH RISK HUMAN PAPILLOMA VIRUS E2 AND E6 GENES FROM CERVICAL CANCER TISSUES. (2022). Academicia Globe: Inderscience Research , 3(11), 35-53. https://doi.org/10.17605/OSF.IO/BQZWV